Dr. Douglas Dluzen

Title: 
Assistant Professor of Biology
Office Location: 
Spencer Hall 111
Email: 
Douglas.Dluzen@morgan.edu
Education:

Ph.D. Genetics, Pennsylvania State University College of Medicine, 2014
B.S. Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, 2007

Education:

Ph.D. Genetics, Pennsylvania State University College of Medicine, 2014
B.S. Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, 2007

Research Interests:

My laboratory is focused on the intersection of human health disparities, aging, and the environment. I'm interested in identifying novel biological and socioeconomic factors that influence health disparities in the community and their impact on healthy aging and age-related diseases. I also study the role of non-coding RNAs in the biology of human aging and am working on identifying non-coding RNA biomarkers that can prevent or contribute to the alleviation of health disparities. My laboratory also investigates the roles of bacteria and other environmental bio-factors, including pollution, on human health and aging in the community.

  • Health disparities in age-related diseases
  • Genetics of healthy human aging
  • Genetics of age-related human diseases
  • Non-coding RNA expression and regulation
  • MicroRNA functionality and gene regulation 
  • Serum biomarkers of aging 
  • Bioenvironmental impact on aging
  • Bioenvironmental impact on health disparities 
  • Bioinformatic data analysis

Courses Taught:

  • Biology 106: Introductory Biology for Majors II
  • Biology 639: Fundamentals of Bioenvironmental Sciences

Selected Publications (Total Publications: 11; Citations: 175):

  • Dluzen DF*., Kim Y*., Basian P., Zhan Y., Lehrmann E., Becker KG., Noren Hooten N., Evans MK. MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation, Oxidative Medicine and Cellular Longevity 2017; accepted.
  • Dluzen DF., Noren Hooten N., Zhang, Y., Kim, Y., Glover, F., Tajuddin, SM., Jacob, K., Zonderman, AB., Evans MK. Racial differences in microRNA and gene expression in hypertensive women. Scientific Reports 2016; 6, 35815.
  • Dluzen DF., Noren Hooten N., and Evans, MK. Extracelluar RNA in aging. WIRES RNA 2016; doi: 10.1002/wrna.1385.
  • Dluzen DF., Sutliff, AK., Chen, G., Watson, C., Ishmael, FT., Lazarus, P. Regulation of UGT2B expression and activity by miR-216b in liver cancer cell lines. J Pharmacol Exp Ther 2016; 359(1), 182-193. 
  • Noren Hooten N., Martin-Montalvo A., Dluzen DF., Zhang Y., Bernier M., Zonderman AB., Becker KG., Gorospe M., de Cabo R., Evans MK. Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence. Aging Cell 2016; 15, 572-581.

Links: