Gloria Hoffman

Title: 
Professor
Office Location: 
Dixon 222
Phone: 
443.885.3070
Email: 
gloria.hoffman@morgan.edu
Education:

MS, PhD, Pharmacology, Universtiy of Illinois Medical School, Chicago
Postdoctoral Fellowship, Anatomy, University of Rochester 

Education:

MS, PhD, Pharmacology, Universtiy of Illinois Medical School, Chicago
Postdoctoral Fellowship, Anatomy, University of Rochester 

Dr. Gloria Hoffman has, for more than 30 years, devised and used immunocytochemical approaches to study functional changes in the nervous system due to genetic factors, physiological state or disease. She directed imaging cores in Rochester, Pittsburgh and at the University of Maryland, and was a part of a project with Dr. Karen Usdin at NIDDK characterizing the CNS problems of the Fragile X premutation using a knock-in mouse model and described the initial neuropathology, behavior and ovarian pathology in those mice.

She also helped characterize the mice with knock-out of the kisspeptin gene, mice lacking components of the JAK3 signaling pathway and other mouse lines with altered brain function. Her laboratory developed new methods for immunohistochemistry and described, for the first time, expression of immediate early genes as markers of stimuli to the reproductive neuroendocrine axis. Some current efforts are directed toward examining molecules involved in neuronal plasticity and the behavioral consequences of mutations in reproductive neuroendocrinecircuits.

Currently, she conducts training workshops in the USA, Mexico and South America to teach approaches to the localization of proteins and mRNAs. Her laboratory has trained 3 high school students, one of which is currently pursuing a career in pediatric cardiology at the University of Pennsylvania; 2 Masters students, 7 PhD students, 13 postdoctoral fellows and multiple investigators and technicians from around the world.